Corner Of Third Ave S And First St S - From I-275, Head South And Take Exit 23B For I-375 E/Baywalk. Merge Onto I-375 E And Continue To The End Of The Expressway. Turn Right Onto 4Th Avenue S, Then Left Onto 3Rd Street S. Continue Straight, Then Turn Right Onto 3Rd Avenue S. Finally, Turn Left Onto 1St Street S ? Your Destination, 301 1St Street S, Will Be On The Right.